Chan Lab:
Autophagy nutrient sensing
Current Ph.D. Students
Ohood Radhi: Studying the role of ULK1-mediated Xenophagy following infection by methicillin-resistant Staphylococcus aureus. Ohood-Aqeed-Radhi@Strath.ac.uk
Supported by Ministry of Higher Education and Scientific Research, Iraq
Cells below show bacterial transport to lysosomes followed by lysosomal damage detected using Galectin3 (green) following infection with Salmonella typhimurium (DNA stain blue). MRSA infection leads to a distinct profile of trafficking to its lysosomal niche.
Chinwe Nwadike: Studying remodelling of the ULK1 complex in cancer cells subjected to metabolic stress. Chinwendu.Nwadike@Strath.ac.uk Supported by Tertiary Education Trust fund, Nigeria
We see altered profiles of ULK1 associated proteins following different forms of nutrient starvation or hypoxia. We are interested in finding novel complex members.
Chinwe also studies AMPK and ULK1 signalling:
Mahmud Abdullah: Studying ULK1-dependent mitochondrial maintenance following nutrient starvation.
Mahmud.Abdullah@Strath.ac.uk Supported by Lagos State Scholarship Board, Nigeria
Following amino acid starvation, mitochondria undergo hyperfusion to form interconnected networks to avoid mitophagy. We are interested in roles of MTORC1 and ULK1 signalling in this process.
Our previous students
PhD
Leon Williamson, 2015
Laura Gallagher, 2016
Martin Werno (Primary supervisor: Luke Chamberlain), 2015
Rebecca Mitchell (Primary supervisors: Gudmundur Helgason, Tessa Holyoake), 2016
Masters
Scott Davidson, 2012
Catriona Crossan, 2013
Raul Berrocal Martin, 2013
Mayulu Mayumbe Chaplin, 2013
Ross Kerr, 2016
Oluwafolabomi Shonubi, 2017
Exchange and ERASMUS
Pavla Zálešáková (Veterinární a Farmaceutická Univerzita Brno), 2011
Ana Cláudia Lima (Universidade do Porto), 2012
Sarah Milar (University Skövde), 2012
Benjamin Pelka (Universität Hamburg), 2013
Rocio Candorcio (University Complutense Madrid), 2017
Undergraduate and Summer Projects
Mark McVicar, 2010
Sarah Millar, 2010
Callum Collins, 2011
Chris Blain, 2011
Haddon McPherson, 2011
Lauren Craig, 2011
Amena Al-Janabi, 2012
Gillian Belbin, 2012
Bianca MacLachlan, 2012
Jo Yu Ho, 2012
Katherine Henderson, 2013
Leanne Ritchie, 2013
Kirsten Geals, 2013
Peter Anderson, 2013
Rachel Wood, 2013
Claire McIntyre, 2014
Teresa Christ, 2014
Kayleigh Hogg, 2014
Godwin Tong, 2015
Lewis Harkins, 2015
Lindsey Bennie, 2015
Shatha Younis, 2015
Julie Nicoll, 2016
Craig Polonis, 2016
Rebecca Orr, 2016
Caroline Summers, 2016
Rachel Wilson, 2016
Matthew Gillespie, 2017
Caroline Douglas, 2017
Roisin McMorrow, 2017
Gillian Berrie, 2017
Claire Carlin, 2017
Metaxo Kyriakou, 2017
Daniel Barclay, 2018
Jia Li, 2018
Yimin Mao, 2018
Cameron Wan, 2018
Kristina Cerniauskaite, 2018
Ewan Murphy, 2018
We are based at the University of Strathclyde, Institute of Pharmacy and Biomedical Sciences in Glasgow, Scotland.
Summer 2018:
We are relocating to Queen’s University
Department of Biomedical and Molecular Sciences,
Department of Pathology and Molecular Medicine. Kingston, Ontario, Canada.
