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From sea-bed to test-bed: harvesting the potential of marine biodiversity for industrial biotechnology

SeaBioTech is an EU-FP7 project designed and driven by SMEs to create innovative marine biodiscovery pipelines as a means to convert the potential of marine biotechnology into novel industrial products for the pharmaceutical (human and aquaculture), cosmetic, functional food and industrial chemistry sectors. To achieve its goals, SeaBioTech brings together complementary and world-leading experts, integrating biology, genomics, natural product chemistry, bioactivity testing, industrial bioprocessing, legal aspects, market analysis and knowledge exchange.

Organisation 

  Country Type of organisation

Strathclyde University

SIPBS

UK

Education establishment

Ingenza

IGZ

UK

SME

Prokazyme

PKZ

IS

SME

Marine Biopolymers

MBL

UK

SME

Pharmaq

PHARMAQ

NO

SME

Axxam

AXXAM

IT

SME

Horizon Discovery Ltd.

HDL

UK

SME

Matis

MATIS

IS

Non Profit Organization

Lund University

LU

SE

Education establishment

Wuerzburg University

UWUERZ

DE

Education establishment

Hellenic Center for Marine Research

HCMR

GR

Research Organisation

Scottish Association for Marine Science

SAMS

UK

Research Organisation

Technical Research Centre of Finland

VTT

FI

Research Organisation

Novamen

NOVAMEN

FR

SME

 The Work Packages

 
work packages

interactions

 

challenges  

Concept of SeaBioTech  

 

SeaBioTech, an integrated approach on marine biodiscovery pipelines: the project’s innovation is at two levels. The first level corresponds to scientific, technical and technological challenges, and includes:

Challenge 1: The approach to resource quality will begin by standardizing the sampling process from unique and previously untapped habitats, including geothermal intertidal biotopes in Iceland, hydrothermal vent fields and deep sea oligotrophic basins of the Eastern Mediterranean Sea, and unsampled areas of Scottish coasts that are likely to be highly productive sources of new bioactive compounds. The SeaBioTech sampling process will guarantee the quality of marine resources for further industrial development, including identification of marine microorganisms and their variability based on genomics and metagenomics. This project will also integrate the critical aspect of the maintenance of the sampled species with their intrinsic quality and their secondary metabolites, by developing special cultivation media and storage conditions.  

Challenge 2: The improvement in technical aspects: to improve marine biodiscovery and reassure industries about its feasibility, SeaBioTech will perfectly combine metabolomics assisted by systems biology and functional bioassays to increase the ability to uncover positive hits with a cheaper and faster approach: an affordable, innovative and efficient method to separate, elucidate the structure, and identify the bioactive metabolites.

Challenge 3: Sustainable modes of supply of raw materials for the industries: The last technical brick for industries is the sustainability of these newly discovered raw materials not only at lab scale but also at industrial scale. Thus, SeaBioTech will benefit from the power of well-controlled metabolic engineering of interesting organisms (bacteria, microalgae, cyanobacteria) to increase the yield of bioactive metabolites at lab scale and multiply this yield through fermentation technology at industrial scale to deliver promising enzymes, polymers and small molecules as industries need.

Challenge 4: The whole biodiscovery process is completed by the clarification of all legal aspects to gain visibility and efficiency for industries. SeaBioTech will perfectly coordinate the legal procedures with national, European and international authorities/stakeholders to propose harmonization of the legal process related to marine bioprospecting, biodiscovery and marine biotechnology for commercial purposes.

Challenge 5: To crystalize this innovative approach, SeaBiotech will create a centralized tool to describe the whole marine biodiscovery pipeline including available biobanks, the identified marine organisms, compounds and extracts, the cutting-edge methods in identification, elucidation, metabolic engineering to be further used for industrial purposes with all related procedures on legal process for companies, academia, and legal authorities.

 

 

SeaBioTech is funded by the European Commission within its FP7 Programme, under the thematic area KBBE.2012.3.2-01 with Grant Number 311932.

 

News

SeaBioTech takes part in Glasgow Science Festival
SeaBioTech invites the public to experience the importance of marine life and research for our environment. Interactive exhibits will be open for kids of all ages at the Strathclyde Institute of Pharmacy and Biomedical Sciences..... more

Ocean medicine hunt: A Wild West beneath the waves?
By Rebecca Morelle
Science correspondent, BBC News, Oban, west Scotland
http://www.bbc.co.uk/news/science-environment-27295159.... more

Meetings

Glasgow hosts 9th ECMNP in 2015
SeaBioTech along with PharmaSea and Bluegenics won the bid to host the 9th ECMNP 2015 in Glasgow. ECMNP2015 will be organised by four Scottish Universities along with the Phytochemical Society of Europe.... more

SeaBioTech 2014 Annual Meeting
Matis will be hosting the 2014 General Assembly in Reykjavik, Iceland.... more