Image Credit: ARTICULAR: ARtificial inTelligence for Integrated ICT-enabled pharmaceUticaL mAnufactuRing (EP/R032858/1).

CMAC are excited to announce the new £1.2M award from EPSRC to lead the new international collaboration for Digital Design and Manufacture of Amorphous Pharmaceuticals (DDMAP).

This award brings together three world-leading research groups from the UK (CMAC, University of Strathclyde), Denmark (CPHarma, University of Copenhagen) and Belgium (CESPE, Ghent University) to deliver a step change in fundamental understanding of amorphous materials that will apply to real industrial challenges in medicines manufacturing. This unique centre will create a dynamic collaboration across Europe that will embrace open science and offer multi-disciplinary and multi-organisational research engagement.

DDMAP has a collaborative mission to develop new science and methodologies that will de-risk the use of amorphous solid forms, reduce the cost of their development and manufacture, and accelerate the adoption of this versatile and effective solid form in the pharmaceutical industry. DDMAP is supported by each of the three leading research groups alongside significant project partners including AstraZeneca, Sandoz and CCDC. The international centre will address key research questions that underpin the selection, production and application of amorphous molecular solids as well as establish a collaborative, world-leading network across Europe with expertise in medicines development and manufacture.

Prof Alastair Florence, PI of the DDMAP international centre to centre award said: “This is a fantastic opportunity to collaborate between three leading centres across Europe and address challenges that limit the more routine exploitation of this important class of pharmaceutical materials. The multidisciplinary team will develop new understanding on the structure, transformations, processing and performance of amorphous systems through a unique international collaboration. Not only will we be building new knowledge, but working together to create an innovative open access data resource that will allow others to benefit from the project as well as supporting the development of the next generation of research leaders in this field.”

The team working to deliver the DDMAP international centre aims include Dr Cameron Brown, Prof Blair Johnston, Dr Andrea Johnston, Dr Daniel Markl and Dr John Robertson (Strathclyde), Prof Jukka Rantanen, Prof Thomas Rades and Prof Anette Müllertz (Copenhagen), and Prof Thomas De Beer and Prof Ashish Kumar (Ghent).

For more information and to find out how to engage with the centre, please contact Prof Alastair Florence: alastair.florence@strath.ac.uk.

Further information on the scheme:
Digital Design and Manufacture of Amorphous Pharmaceuticals (DDMAP) is one of 12 international collaborations to develop the technologies of tomorrow.

https://www.ukri.org/news/international-collaborations-to-develop-technologies-of-tomorrow/