Cardiovascular Sciences

The cardiovascular research programme includes studies of the physiological and biochemical regulation of the cardiovascular system, the pathophysiology of cardiovascular disease, and identification of novel therapeutic cardiovascular targets. Members of the theme have developed a wide range of in vivo models cardiovascular disease including cardiac hypertrophy, cardiac arrhythmias, pulmonary hypertension, stroke, vein graft remodelling, intravascular stents. Facilities include pharmacology, cell signalling, cell calcium imaging, pathology, morphology, cell culture, in vivo imaging, drug delivery to cardiovascular targets, metabolomics, myography. Current projects relate to intracellular calcium, nitric oxide, cardiovascular remodelling and inflammation, oxidative stress, safety pharmacology, receptor pharmacology, culture of clinical cells, patient biomarkers, human cardiovascular physiological measurement.

The Strathclyde Centre for Cardiovascular Research is a virtual centre that brings together the wide range of research activity relevant to cardiovascular research involving staff across the University of Strathclyde and partner organisations. The Centre encompasses studies of animal models of cardiovasculare disease, cardiovascular medical devices, mathematical modelling, and clinical studies. In addition to members from SIPBS the Centre has members from the Department of Mathematics and Statistics, the Bioengineering Department, the Department of Pure and Applied Chemistry as well as Glasgow Royal Infirmary and Glasgow Western Infirmary.

Theme Members
Dr Hilary Carswell, Dr Paul Coats, Susan Coker, Dr Susan Currie, Professor Robert Jones, Professor John McCarron, Professor Roger Wadsworth, Professor Robin Plevin, Dr Charles Kennedy, Professor Susan Pyne, Professor Nigel Pyne, Dr Robert Drummond, Dr Andrew Paul, Dr Edward Rowan, Professor Alex Mullen, Dr Fiona McInnes, Professor William Harnett, Dr Catherine Lawrence, Professor Alan Harvey Dr Debbi MacMillan