Dr John Dempster
B.Sc (Hons), M.Sc., Ph.D.
Senior Lecturer
SIBS 501A
Tel : 0141 548 2320 (Ext. 2320)
Electrophysiology softwareThe Strathclyde Electrophysiology Software package is a set of specialised programs for the acquisition and analysis of signals from electrophysiological experiments. The software development program was started in 1985, as a Wellcome Trust funded project, to satisfy the needs of a number of research groups within the Scottish universities. The software is now widely used in over 500 academic and industrial research laboratories throughout the world. It is provided free of charge to academic and other non-commercial users and licensed to pharmaceutical companies. Specialised data acquisition and analysis software plays a crucial role in state of the art experimentation in the electrophysiological and neuroscience fields. Relatively few laboratories have the skills to develop software to the required standard and, due to the limited size of the market there are few commercial packages. A subtle understanding of the needs of researchers and professional software development skills has proven to be required to produce useful software for this area. The software has been constantly updated over the years to take advantage of developments in personal computers, evolving from a minicomputer-based package, to the current Microsoft Windows-based software. | winWCP
winCDR
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Selected Publications
- MacQuaide N, Dempster J, Smith GL. (2009) "Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes." Biophys J 96 2744-54
- Gelman, A.E., W. Li, S.B. Richardson, B.H. Zinselmeyer, J. Lai, M. Okazaki, C.G. Kornfeld, F.H. Kreisel, S. Sugimoto, J.R. Tietjens, J. Dempster, G.A. Patterson, A.S. Krupnick, M.J. Miller, and D. Kreisel. (2009) "Cutting edge: Acute lung allograft rejection is independent of secondary lymphoid organs." J. Immunol. 182 3969-3973
- Babich V, Knipe L, Hewlett L, Meli A, Dempster J, Hannah MJ, Carter T (2009) "Differential effect of extracellular acidosis on the release and dispersal of soluble and membrane proteins secreted from the Weibel-Palade body." J Biol Chem 284 12459-68
- Babich V, Meli A, Knipe L, Dempster JE, Skehel P, Hannah MJ, Carter T.
(2008) "Selective release of molecules from Weibel Palade bodies during a lingering kiss." Blood
- Mitchell EA, Gentet LJ, Dempster J, Belelli D.
(2007) "GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids." J. Physiol. 583(Pt 3) 1021-40
- MacQuaide N, Dempster J, Smith GL.
(2007) "Measurement and modeling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes." Biophys. J. 93(7) 2581-95
- Michael G, Dempster J, Kane KA, Coker SJ.
(2007) "Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation." Br J Pharmacol. 152(8) 1215-27
- Zinselmeyer B.H., Dempster J., Gurney A.M, Wokosin D., Miller M., Hsiang H., Millington O.R, Smirh K.M, Rush C.M., Parker I., Cahalan M., Brewer J.M, Garside P. (2005) "In situ Characterisation of the Behaviour of Antigen-Specific CD4+ T Cells in Mucosal and Systemic Lymphoid Tissues during the Induction of Oral Priming and Oral Tolerance." J Exp Med. 201(11) 1815-23
- Dempster J, Graham J, Sinclair J, Smith GL, Thomas MV (2002) "Demonstration of integrator unit and data acquisition software for laser-scanning microscopy." J. Physiol 543P S043
- Dempster J, Wokosin DL, McCloskey KD, Girkin JM, Gurney AM (2002) "WinFluor - An integrated system for the simultaneous recording of cell fluorescence images and electrophysiological signals on a single computer system." Br J Pharm 504P P57
- Dempster J (2001) "The Laboratory Computer: A guide for neuroscientists and physiologists" Academic Press, London 354pp
- Dempster J (1993) "Computer analysis of electrophysiological signals. " Academic Press, London 218pp
page last updated: 02/09/2008