

Infection, Immunity and Microbiology Overview Pathogens/model organisms under study: Acanthomoeba, Acanthocheilonema, Aspergillus, Corynebacterium, Escherichia, Leishmania, Myobacterium, Pichia, Pseudomonas, Salmonella, Shigella, Streptomyces, Toxoplasma, Trichomonas, Vibrio. Staff involvedProfessor James Alexander [immunology,vaccinology, Leishmania], Dr Katharine Carter [Leishmania], Professor Graham Coombs [Leishmania, Trichomonas, biochemistry], Dr Geoff Coxon [tuberculosis, medicinal chemistry], Professor William Harnett [immunology, helminthology], Dr Linda Harvey [Bioprocessing], Dr Paul Herron [molecular bacteriology], Dr Paul Hoskisson [bacterial molecular physiology], Dr Hui-Rong Jiang [immunology], Dr Catherine Lawrence [helminthology, mast cells], Dr Alan McCruden [immunology], Professor Brian McNeil [bioprocessing], Dr Owain Millington [immunology, Leishmania], Professor Craig Roberts [molecular parasitology, immunology, Toxoplasma], Dr Dino Rotondo [inflammatory responses], Dr Veronique Seidel [natural products chemistry, antibiotic discovery], Dr Nicholas Tucker [bacteriology, biochemistry], Dr Martin Wiese [Leishmania, protein kinases], Dr Jun Yu [molecular pathogenesis of bacterial infection]. Postgraduate Research OpportunitiesCharacterisation of the Control of Inflammatory Responses in Human Immune cellsMeasuring enzyme activity in Leishmania infected macrophages using SERRS New drugs for bad bugs: Manipulation of antibiotic biosynthetic pathways for better drugs Targeting the nematode carbohydrate: phosphorylcholine transferase Coordination of DNA replication with hyphal growth in the antibiotic producing bacterium Streptomyces coelicolor Determining immune control of infection versus autoimmunity Investigating the distinct roles of dendritic cells and macrophages in immunity using a Leishmania mexicana infection model Developing lab-on-a-chip tools to investigate individual immune cell interactions Role of mast cells in inflammatory arthritis Mast cells in gastrointestinal helminth infection Examining the antibiotic potential of legumes Development of a Mucosal Anti-fertility Device Based on Metal Nanoparticles Understanding metabolic and genetic changes on scale translation of natural isolates |